The Cancer Cell Essay Example | Topics and Well Written Essays - 750 words

The Cancer Cell - Essay Example For an extensive stretch, it has become certain that malignancy much of the time encroaches on residents who are over 50 years. In spite of the fact that the young people likewise gets harrowed with such diseases, most of masses enduring such infirmities as malignant growth is the old people (Hobson, 2009). Through the accompanying perception, analysts have begun to examine the connection between organic methodology that immediate malady and maturing forms. Scientists have to this point had the option to decide the association between the two. Specialists have validated two different ways of review the connection among's malignancy and age. As per the discoveries gave, are that the powers that cause harm to human qualities might be like the powers that urge both disease and maturing (Hobson, 2009). In this way, this recommends the procedures guard against malignant growth, the genome and changelessness. Be that as it may, the subsequent explanation is by all accounts somewhat complex concerning the connection among the two. Normally happening tumor silencer atoms keep the phones from repeating or recovering inconsistently. The tumor silencer cell incites the casualty of the cells through a method viewed as apoptosis or it can close down the cell’s capacity to recreate. These two movements delivered by the silencer particles serve to secure the individuals during their conceptive periods. In this way, as the masses gets more seasoned, the particles capacities to watch the body through the two techniques decrease. Hence, the body gets helpless against malignant growth assaults legitimizing the explanation that the disease cases are progressively broad in the elderly folks individuals. For the youthful age, the defenselessness is notably diminished through the activity of the silencer atoms. The more seasoned individuals experience corporal changes that enlarge the likelihood of sickness and incapacity and which meddle with the body’s capacity to wit hstand disease dangers. Malignancy happens principally as a result of any changes or modifications on the oncogenes, tumor silencer particles and microRNA hereditary material (Croce, 2008, 502). These alterations are normally substantial techniques, despite the fact that root transmutation can arrange a person to hereditary or tribal malignancy. In disease, a solitary modification may not be adequate to start malignancy rather, disease advancement is a multistep movement with changes happening in oncogenes (Croce, 2008, 502). Oncogenes are proteins that foreordain for the control of cell proliferation, apoptosis or even the two procedures. These qualities are initiated by auxiliary changes that begin from transformations or intensification (Croce, 2008, 503). Chromosomal redesign, transmutations and quality expansion, help in actuation of oncogenes introducing an augmentation advantage or intensified proceeded with presence of cells bearing such varieties. In situations where, the o ncogenes are initiated by transformations, the preset protein is changed fundamentally in manners that take into consideration its changing activity. Myc is a replication controller and its qualities are generally translocated from the first chromosome to another chromosome. Chromosomal translocations help in combining the cell oncogene with immunoglobin that are accepted to be indispensable, in the commencement of the oncogenic movements in the improvements of certain cell types. The translocation can be viewed as fundamental basically, that it helps in the investigation of the methods, heredity and organic results of the translocations.

Herpes Essay -- essays research papers

Herpes Herpes is one of the regular of in excess of 30 distinctive explicitly transmitted maladies (STD’s) in America today. Herpes is a disease that is brought about by one of two firmly related infections, herpes simplex infection type 1 (HSV-1) and herpes simplex infection type 2 (HSV-2). The two of which are effectively gotten, have comparable side effects, and can happen on various pieces of the body. Despite the fact that it is generally normal to see the infection HSV-1 show up as oral herpes and to see the infection HSV-2 show up as genital herpes.      Most regularly herpes is a generally innocuous sickness that is once in a while hazardous. The most widely recognized type of herpes is oral herpes and for the most part appears on the lips or within the mouth as â€Å"cold sores† or â€Å"fever blisters†. Mouth blisters are regular in little youngsters who obtain them from being presented to dynamic mouth blisters of grown-ups and other kids. This type of herpes is irritating yet innocuous in the two kids and grown-up, yet is anyway extremely hurtful to an infant. It can here and there be hard to recognize whether somebody has been presented to the next type of herpes, genital herpes. This is on the grounds that there are all the time no side effects that accompany the infection. This isn't generally the situation however and when side effects do happen they are regularly observed as a bunch of rankle wounds, as a rule on the vagina, vulva, cervix, penis, or butt. For genital herpes, side effects may mos t recent half a month, leave yet just to return again weeks, months, or even years after the fact. Indications may a...

New Student Photo Series #7 COLUMBIA UNIVERSITY - SIPA Admissions Blog

New Student Photo Series #7 COLUMBIA UNIVERSITY - SIPA Admissions Blog Were only a few days from Orientation.   Students are stopping by the office to introduce themselves.   And even though this new class is just starting, we feel like theyve been around for a while.   Weve gotten to know them during the admissions process so its very exciting to finally see all of them in person. As we count down to Orientation, well post the rest of the photo contributions from our new students so you may share their adventures before arriving at SIPA. Our next submission comes from Bartosz Garbaczewski who will be pursuing his Master of International Affairs, concentrating in Energy and Environment and specializing in Advanced Economic and Policy Analysis. *** This coming September I will officially join the family of  Columbia University | SIPA a family of incredibly diverse backgrounds and experiences! I look forward to meeting you all, and sharing personal interests and passions, as well as  professional experiences in and beyond classrooms.   As we all arrive in NYC and arrange for housing for the upcoming academic year, here are some facts about myself, which I would like to share.   I am originally from Poland where I spent the first twenty years of my life. Since the last nine years I studied, worked and lived in six countries around the globe including Germany, England, China, Canada, the Netherlands, and Qatar. My professional experience is in the energy industry, where I have spent four years working across downstream and upstream businesses in one of the worlds largest oil majors.   As a keen traveler, I am sharing three photographs, which I took in Qatar, Thailand and most recently in Sri Lanka. Cheers,   Bartosz Qatar : Stopping for a picture with camels in Al-Shahaniya in Qatar in March a place where every visitor should stop to catch a camel race during the season Sri Lanka : Stilt fishermen fishing from their poles in Unawatuna in Sri Lanka presented a view worth capturing with my camera this July Thailand : While visiting Thailand in May I visited Damnoen Floating Market one of the most famous Thailands floating markets.

Pelican Bay State Prison s Racial Base Classification System

Introduction Prison classification is an important process in the U.S. correctional system and community corrections. Every state utilizes different types of classification method to classify their inmates. Penal institutions in the U.S. have evolved tremendously in terms of sentencing procedures, decisions and classifications. Studies from Clear et al. (2013) indicate that offenders in the United States, which consists of men, women, and juveniles, were all confined together in the same prison in the early 1800’s (p. 296). Modern correctional facilities do not mix the entire population of men, women, and juvenile offenders in the same jail or prison, but rather, in separate correctional facilities with different levels of security and monitoring. In our current era, correctional facilities for men, women, and juveniles have rehabilitative programs and modern identification systems that have the capability to measure â€Å"static risk factors such as criminal history or severity of curren t crime† (Christensen, 2008, p. 18). This case study will examine Pelican Bay State prison’s racial base classification system, and whether its practices are considered as a violation of an inmate’s civil rights. Analysis Tucked in California’s remote northwest coast lies a state penitentiary called Pelican Bay, which is known for its’ notorious isolation unit that houses the most violent criminal offenders in the United States. Pelican Bay operates on a coding system called racial

Certainty in Descartes Meditations on First Philosophy...

Certainty in Descartes Meditations on First Philosophy Renà © Descartes was the first philosopher to raise the question of how we can claim to know anything about the world with certainty. The idea is not that these doubts are probable, but that their possibility can never be entirely ruled out. If we can never be certain, how can we claim to know anything? The First Meditation of Meditations on First Philosophy, subtitled What can be called into doubt, opens with the Meditator reflecting on the number of falsehoods he has believed during his life and on the subsequent ability of the body to deceive him. Seated alone by the fire, he resolves to demolish former opinions and rebuild his knowledge on more certain grounds. The†¦show more content†¦However, the Meditator realizes that he is often convinced when he is dreaming that he is sensing real objects. He feels certain that he is awake and sitting by the fire, but reflects that often he has dreamed this very sort of thing and been thoroughly convinced by it. On further reflection, he realizes that even simple things can be doubted. Omnipotent God could make even our conception of mathematics false. One might argue that God is supremely good and would not lead Descartes to believe falsely all these things. He supposes that not God, but some evil demon has committed itself to deceiving him so that everything he thinks he knows is false. By doubting everything, he can at least be sure not to be misled into falsehood by this demon. Recalling his previous thoughts in Meditation Two, the Meditator supposes that what he sees does not exist, that his memory is faulty, that he has no senses and no body, and that extension, movement and place are mistaken notions. Perhaps, he remarks, the only certain thing remaining is that there is no certainty. Although this argument often seems logical and fully-developed, Descartes uses this meditation to as inspiration prove that perhaps there is one thing that is absolutely certain in the universe: his existence. The Meditator has conceded that he has no senses and no body, but can he not exist either? He has also noted that the physical world does not exist, which might also seem to imply his non-existence. Yet toShow MoreRelatedDescartes Six Meditations on First Philosophy Essay1347 Words   |  6 PagesThroughout the six meditations on First Philosophy, French philosopher Rene Descartes seeks to find a concrete foundation for the basis of science, one which he states can only include certain and unquestionable beliefs. Anything less concrete, he argues will be exposed to the external world and to opposition by philosophical sceptics. The sense of the Cartesian reform is the imposition of a new method of thinking. Descartes’ method to begin with is reductive, removing all knowledge acquired withoutRead MoreThe Nature Of The Human Mind878 Words   |  4 PagesRene Descartes second meditation is titled, Concerning the Nature of the Human Mind: That it is Better Known than the Body. In his second meditation, Descartes argues that the human mind exists merely by itself without any physical representation in the world. This argument lead to many of his later meditations and allowed him to really build the framework for Western Philosophy. The cogent argument is arguably the most crucial argument, which lead us to our philosophy of the mind. In some respectRead MoreArguments For The Existence Of God1137 Words   |  5 Pagespersonal experience, and some on philosophy. Descartes offered two arguments towards the existence of God: an informal proof in the third meditation and the ontological proof in the fifth me ditation. Descartes believed that with the employment of a rational method of inquiry which applied some of the methods of analytic geometry to the study of philosophy, our ability to attain certainty and validity about our knowledge would be greatly increased. For Descartes to include a second and distinct proofRead MoreDescartes Meditations On First Philosophy1318 Words   |  6 PagesPhilosophical Questions November 2, 2017 Cogito Ergo Sum Descartes Meditations on First Philosophy and his questioning of our existence in reality is a question which philosophers have tackled throughout time. Cogito ergo sum or I think therefore I am, a phrase brought about by Descartes is the backbone of his whole philosophy of our existence in reality. As long as we are thinking things, we exist. When we look at this approach to our existence we must first deny that any sensory data that we receive is believableRead More Rene Descartes Essay1094 Words   |  5 PagesRene Descartes was a famous French mathematician, scientist and philosopher. He was arguably the first major philosopher in the modern era to make a serious effort to defeat skepticism. His views about knowledge and certainty, as well as his views about the relationship between mind and body have been very influential over the last three centuries. Descartes was born at La Haye (now called Descartes), and educated at the Jesuit College of La Flà ¨che between 1606 and 1614. Descartes later claimedRead MoreDescartes Meditations On First Philosophy1712 Words   |  7 PagesDescartes’ Meditations on First Philosophy (1641) contains six Meditations. In the first two of these Descartes addresses doubt and certainty. By the end of the second Meditation Descartes establishes the possibility of certainty by concluding that he is a â€Å"thinking thing† and that this is beyond doubt. Having established the possibility of certainty, Descartes attempts to prove the existence of God. The argument he presents in the Third Meditation for the existence of God has been nicknamed theRead MoreDescartes and God Essay820 Words   |  4 PagesDescartes and God Everywhere in this world there are debates on many things. Logic is often employed in order to understand and come to an agreement on these debated topics. One such topic, which is arguably the greatest topic of debate occurring in modern day, is the existence of God. Sure, many people believe in some sort of higher being, but how many of them try and use logic and rational thought to prove the existence of God. Many probably, however we will only look at one such person.Read MoreRene Descartes And Kant1013 Words   |  5 Pageswith many philosophers worth studying, a common theme present amongst Renà © Descartes, David Hume, and Immanuel Kant is the fact that all three philosophers challenged the traditional ways of thinking about philosophy respective to their eras. In certain aspects, all three of these philosophers also grappled with understanding, discovering, and logically explaining the power of the mind to shape whole truths. From Descartes’ foundational work with me thodological doubt to Kant’s contribution to previousRead MoreEssay about Descartes View on the Senses652 Words   |  3 PagesDescartes first meditation included a few arguments that Descartes studied and analyze. The one I choose to analyze was his argument of sense deception. The actually argument is the following: (1) My senses sometimes deceive me. (2) If my senses sometimes deceive me, then they might always deceive me. (3) If my senses might always deceive me, then I cannot be certain about any beliefs acquired through my senses. (4) If I cannot be certain about any beliefs acquired through my senses, then I mustRead MoreRene Descartes s Meditation On First Philosophy802 Words   |  4 PagesRenà © Descartes objective in Meditation on First Philosophy is to construct philosophy as a solid methodical study and discipline alike the sciences. To do so he must first suspend belief in all things doubtful and from their go about verifying the true concepts of the world. In meditation II he verifies that he is a thinking thing and finds that the certainty of the cogito â€Å"I think therefore I am† lies in the distinct perception of what he affirms. From this he generates a general rule of evidence

Case Study Lonely Free Essays

1. Prepare a report in which you analyze the marketing channel conflicts and cannibalization issues that Lonely Planet faces as it is currently operating. Suggest solutions that might reduce revenue losses or operational frictions that result from these issues. We will write a custom essay sample on Case Study Lonely or any similar topic only for you Order Now Channel Conflict: when sales through the company’s web site interfere with sales in that company’s retail stores. The potential for significant channel conflict exists in Lonely Planet with the same product (books or content) being sold via multiple channel. Lonely Planet has worked hard to minimize channel conflict by selling books on their website only at the recommended retail price, therefore it does not undercutting their retail resellers. Moreover, most retailers hold only a small selection of the five hundred Lonely Planet titles, and for the many titles they do not hold, channel conflict is minimal. The CitySync product is also carefully positioned to reduce channel conflict, since it targets a specific segment (time-poor, cash-rich travelers) with a new offering that is somewhat different from the existing Lonely Planet city guidebooks. However, over time there may be some conflict between CitySync and products such as customized guidebooks. Cannibalization: The loss of traditional sales of a product to its electronic counterpart. The well-known travel guides company, Lonely Planet gives a lot of guides for free on its website. A few years ago, many major travel-guide publishers were concerned that Lonely Planet website will hurt their sales. If travelers have to travel on board, they could just go on the website in order to read all the information they need without buying the Lonely Planet travel guide paper version. But far from cannibalizing sales instead, the net has helped publishers build their brands and expand into new territory. Moreover, giving information on its own website is a way to do free advertising. Without this display of guides on the website, customer would not have bought the travel guide paper version. Lonely Planet and other leading publishers have recorded growth rates of 15% to 25% per year over the past four years, as much as their guidebook content has migrated online. 2. Prepare a list of a new products that Lonely Planet might introduce to take advantage of Internet technologies (including wireless technologies for mobile devices) and address customer’s concerns about the timeliness and currency of information in the printed travel guides. Briefly describe any problems that Lonely Planet will face as it introduces these new products. In 2008, Lonely Planet launched Pick Mix which enables travelers to go to a section of the Lonely Planet Website ( http://shop.lonelyplanet.com), select the country or region to which they are travelling and download the chapter for the place they are visiting. Rather than carry loose pages, chapters (served as PDF files) can be downloaded into a hand-held device or e-book reader. Interactive e-book travel guides: Emerging the best of both medium – digital and print – into one interactive ebook guide. Lonely Planet introduced e-books on ipad, so the layout and design is to flip through a guidebook and includes signature stunning images, expert author content and tips from local. Unlike traditional print guide book, the digital format allows to include over 3,000 hyperlinks so readers can get to a particular chapter or map with just a tap of a finger. Thus, travelers can get information on a particular region, point of interest or hotel/ restaurant without flipping through the pages. More, travelers can search terms in Google or Wikipedia for additional content. Travelers can also bookmark the places they don’t want to miss and make notes on the page, just like a print guidebook. Usually traditional publishing cycle for the print guides is every 2 years, but with e-books, it will be updated in a real time. However, unlike apps, ebook updates are not pushed out to end user, and readers will have the opportunity to repurchase the new edition. In addition, due to handheld’s limited memory and bandwidth, the new applications focus on cities, not countries. They obviously can not replace a guidebook for a month-long odyssey in Thailand or an exploration of Italy’s Amalfi Coast. Â  But for the traveler who wants to figure out how to spend a free afternoon or where to go for dinner, these mobile guides – plus a good map are ideal substitutes for printed guides. Lonely Planet therefore should continue to invest in product development to work with the likes of Apple, Google, Amazone, Nokia, etc. 3. Many loyal Lonely Planet customers carry their travel guides (which can be several hundred pages thick) with them as they travel around the world. In many cases, these customers do not use large portions of the travel guides. Also, Internet access can be a problem for many of these customers while they are travelling. Describe a product (or products) that might address this customer concern and also yield additional revenue for Lonely Planet. Your answer here could build on ideas that you developed in your solution to part2. By using interactive ebook travel guides, travelers doing longer trips do not need to carry three or four guidebooks during travelling. Travelers can buy the content directly and save it in their hand-held or ebook before they are going to travel on board if the current destination does not provide good internet connection. It is also an ease to carry around. Moreover, travelers can bookmark the places they don’t want to miss and make notes on the page, just like a print guidebook. How to cite Case Study Lonely, Free Case study samples

Bravery Essay Example For Students

Bravery Essay My quote has to do with an emotion every person and every living thing feels. My quote has to do with fear. My quote isnt just about fear its self, it has to do with what it takes to get through fear, and to get through fear you have to have courage and when you have courage you are brave. My quote is about being brave. You cannot be brave unless you feel fear. by Francine Pascal. People can be brave in so many ways, just by overcoming a simple fear. For example, the dark can arouse fear in the hearts of many especially for a five year old boy. Imagine that five yr old boy, and imagine him having an extremely snotty older brother that radiates with an I fear nothing ora. Then imagine all the terrifying things that scared you when you were five, especially the dark. One night when its time for him to go to bed his older brother snickers and says Nice nightlight baby as he walks by his room thats glowing from the train light nightlight that plugs into his wall. We will write a custom essay on Bravery specifically for you for only $16.38 $13.9/page Order now So wanting desperately to be just like his older brother the little boy climbs out of bed, snatches the night light and runs as fast as his five year old legs can carry him. Now the dark surrounds him and he feels the monsters that inhabit his closet creeping out craving little boy toes. He runs much faster and with a mighty leap he lands safely in his bed. A warm feeling flows through his body as he pulls the sheets up to his chin for extra protection. That warm feeling is the feeling of being brave. Another example of Bravery Essay I can give you is me. At the end of my sophomore year in high school me and two of my friends made a very dumb decision, well a couple of dumb decisions. We choose to drink one night, but also we choose to drive. As a consequence to our stupidity one of my best friends Chelsea Clark lost her life. I was so scared to see the faces of the kids at my school and most of all Chelseas friends. I dont know how but somehow I overcame that fear and had to go on with life even though Chelseas was over. I guess you could call that being brave. In some way, big or small, deep or shallow, everything in life has a lesson that can be learned from it. This quote was not a lesson on how to be brave or what you should do or say to be brave, but I think it was a lesson in a way on why people are brave. This quote You cannot be brave unless you feel fear. by Francine Pascal, is about what exactly it is to overcome fear. Bibliography: . Bravery Essay Example For Students Bravery Essay What is the first thing that comes to mind when the word Bravery Essay is said? For most people a war hero or a superhero comes into their minds. Probably every language has a word for bravery, but there is only one true meaning. The word bravery is showing a brave spirit or courage(Random, p. 164) when hard times are thrust upon or happen to them. Bravery is not only what people do, but how they do it. The concept is also showiness, splendor, and magnificence(Random, p. 164). Bravery may be shown in different ways: a person may jump from a plane or walk on fire to show that he/she is truly brave. Then again, sometimes bravery is something that a person has inside him or her and is never shown as an action at all. For thousands of years, people have used words that describe the concept of bravery. The history, or etymology, of the English word bravery is as follows. We will write a custom essay on Bravery specifically for you for only $16.38 $13.9/page Order now The word originated in Latin as barbarus. The Romans who spoke Latin were warriors so it is logical they would have a word that talked about their courageous actions. The Vulgar Latin, which was spoken Latin, was transformed by Middle French in the Middle Ages as well as by Middle English. This form of English was what was spoken in the 12th to 15thcenturies. From the Middle English evolved the English we speak today and with it, the word bravery. Throughout history, people have talked about the concept of bravery in many ways. The Greek writer and philosopher Euripides said, The man who knows when not to act is wise. To my mind, bravery is forethought (Euripides, p.11). In the Middle Ages, George II of England said that bravery never goes out of fashion (George, p. 261). Later, Francois de la Rockefoucould said, True bravery is shown by performing without witness what one might be capable of showing all the world (Rockefoucould, p. 12). Bravery has seemed to be an important concept or action throughout history. When Francois de la Rockefoucould spoke about bravery, he pointed out an important feature of the virtues true meaning. Then he made the distinction between peoples private actions versus their public ones, he made it clear that people who do good deed only to get rich or famous are not practicing bravery. True bravery is helping people or animals simply because their actions benefit mankind. It seems that we often misunderstand this aspect of bravery and make the wrong people famous while forgetting about others who show bravery throughout their lives. The one person that, for me, most represents bravery in this century is Martin Luther King, Jr. Mr King was born in Atlanta, Georgia when black men and white men did not mix. When he died, these two races were a little closer to peace. This was due primarily because of the great influence that Martin Luther King, Jr. had in the United States. He got on the bandwagon of the civil rights movement with the Montgomery Bus Boycott. He kept leading the movement after his house was bombed. That was bravery because he put his life on the line to make all American black peoples lives better. Later in his life, in 1963, he and other protesters in Birmingham, Alabama, were met by police with dogs and high pressure water hoses (Norell, np). This event was shown on television. His resistence in Alabama was brave because when police came, he and the others did not back down but rather stood up for their beliefs. I dont know if Ive shown bravery or not in my life yet. .u24861c2a64c0b4e7f8837b6e80a4e537 , .u24861c2a64c0b4e7f8837b6e80a4e537 .postImageUrl , .u24861c2a64c0b4e7f8837b6e80a4e537 .centered-text-area { min-height: 80px; position: relative; } .u24861c2a64c0b4e7f8837b6e80a4e537 , .u24861c2a64c0b4e7f8837b6e80a4e537:hover , .u24861c2a64c0b4e7f8837b6e80a4e537:visited , .u24861c2a64c0b4e7f8837b6e80a4e537:active { border:0!important; } .u24861c2a64c0b4e7f8837b6e80a4e537 .clearfix:after { content: ""; display: table; clear: both; } .u24861c2a64c0b4e7f8837b6e80a4e537 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u24861c2a64c0b4e7f8837b6e80a4e537:active , .u24861c2a64c0b4e7f8837b6e80a4e537:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u24861c2a64c0b4e7f8837b6e80a4e537 .centered-text-area { width: 100%; position: relative ; } .u24861c2a64c0b4e7f8837b6e80a4e537 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u24861c2a64c0b4e7f8837b6e80a4e537 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u24861c2a64c0b4e7f8837b6e80a4e537 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u24861c2a64c0b4e7f8837b6e80a4e537:hover .ctaButton { background-color: #34495E!important; } .u24861c2a64c0b4e7f8837b6e80a4e537 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u24861c2a64c0b4e7f8837b6e80a4e537 .u24861c2a64c0b4e7f8837b6e80a4e537-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u24861c2a64c0b4e7f8837b6e80a4e537:after { content: ""; display: block; clear: both; } READ: Martin Luther King Jr. Dream Speach Essay I havent had any opportunities to save anyone or make a difference in the world. There have been times when I have stood up for my beliefs or said what I thought was right when it meant that I might not get to do something. I think Ive been brave in these situations but to talk about what Ive done and compare it to the actions of a man like Martin Luther King, Jr. is to compare apples and oranges, to make my actions greater than they were or to make his actions less important than what they have been .

Orrin Johnson Essays - English-language Films, Of Mice And Men

Orrin Johnson 10/12/98 Lit The Mouse of all men The book I read was Of Mice and Men by John Steinbeck. Of Mice and Men is a great book. It shows how loving somebody so much could also mean doing anything for them, even murder them. Best friends George and Lenny travel around looking for work, only so they can get money so they can have there own farm and a house on a nice huge size piece of land. They finally find a good job were they can make some money but, unfortunately Lenny messes up and gets George kicked out of the town. So they go somewhere else on the other side of town and they get back in a job but, Lenny messes up again. While Lenny was talking to the job owner's wife his wife asked him to fell her dress. Lenny liked her dress because of the way it felt. But when she asked him to stop he wouldn't so she started to scream. Lenny did not want her to scream so he covered her mouth thinking she would stop screaming. What happened was he killed her by suffocation. Lenny freaked so he put her body in the trashcan trying to hide it. When the owner found the body him and his friends formed a mob and were going to find Lenny and kill him brutally. When Lenny found out he ran away to the place were George told him to go if he ever got in trouble. So when everybody went looking for him George already knew where he was. When George found him he had a gun. George turned him around slowly and told him the story about the land, the farm, and the rabbits of all colors. In a split second Lenny was laying face down in the sand. George had killed him. The two main characters are George and Lenny. George is the discipline of the crew. Kind of like a father to figure you might say. Lenny on the other hand has a mental status that the two never talk about because of Lenny. He may have the mental status and all but, He loves to have fun. Of Mice and Men takes place in Salinas, California during the Great depression. Steinbeck described it as a hot calm place, with Weeds and corn field all over. Almost like an old western. The theme of this book really is about love. This book shows How you can love someone so much you would even take his or her life. Not just take their life because you don't love them or what ever, But to save them from a mob of men out to torture and kill them. A decision like the one George had to make is one of those once and a life time things that come to some people, and only sometimes. Leone and George are two men who don't want much in life But, a farm and each other so they can live off the fatta the land. This farm will consist of rabbits and only rabbits of all colors. Although this dream for them never comes true they, were on there Way to it. I recommend this book to anyone who likes non-fiction book that talk about life and friends.

Biblical Word Study

Biblical Word Study Abstract This paper develops a study of selected words from the bible. Under the counseling category, the paper examines the meaning, usage and derivatives of the words counsel, wisdom and help. Under the addiction category, the study examines the meaning, derivatives and usage of the words wine, desire and restraint.Advertising We will write a custom critical writing sample on Biblical Word Study specifically for you for only $16.05 $11/page Learn More The study seeks to examine the usage of the words in the old and new testaments, which are arranged in different paragraphs for every word. Biblical words related to counseling This section examines the biblical usage of the words counsel, help and wisdom. The Blue Letter Bible, a resource site that provides links to other bible versions, is used as the primary study material. Through this site, the study examines the usage of these words in the New American Standard Bible, King James Version and the New King James Version Bibles. Counsel In the bible, the word counsel is the Aramaic translation of ‘dethabar’ in the Old Testament and the Greek word ‘bouleutes’ in the New Testament. In addition, it is the translation of the Hebrew word ‘etsah’ or ‘atsa’. Usage in the Old Testament The word counsel has a number of meanings applied to it in various cases. In other cases, the word is used to mean purpose, devise, and plan or to counsel. The first appearance is in Exodus 18:19, where Jethro was advising Moses to be the people’s representative before God, taking their disputes to Him. Usage in the New Testament There are only two instances of the word counsel in the New Testament. In Zechariah 6:13, the word is used to mean perfect harmony or peace. In Ephesians 1:11, the word counsel is used to mean ‘guidance of the Lord’s plan† (New King James Version Bible, [NKJV], 2011) Wisdom The word wisdom is used to mean kno wledge, understanding or excellent ability to apply knowledge or understanding.Advertising Looking for critical writing on religion theology? Let's see if we can help you! Get your first paper with 15% OFF Learn More Usage in the Old Testament In the Old Testament, the word is mostly used in Job, proverbs and psalms. For instance, it is used to mean human knowledge or understanding of an idea. In Exodus 35:31, it is used to mean excellent human understanding or experience with a subject. This is also similar in a number of other instances where it is used (American Standard Edition [ ASV], 1901). In job 32:13, the speaker says â€Å"we have found wisdom† while in Job 33:33, the speaker says â€Å"keep silent so that I can teach you wisdom† (King James Version [ KJV], 2000). These cases show that the word also means knowledge obtainable through learning and teaching (Tan, 2011). Usage in the New Testament The word also appears several times in t he New Testament. Like the Old Testament, the word is used to have similar meanings in the New Testament. It is used to mean knowledge, excellent experience with a subject or the right ideas that reside in humans. For instance, in Mathew 13:54, it is used describe the extraordinary knowledge expressed by Jesus as â€Å"where did this man get this wisdom and powers from?† (New American Standard Bible [NASB], 1995) Help This word appears 147 times in the NASB and is used several times in both testaments. In most cases, it is used to mean any form of aid that a person or group of persons can obtain from another person, group or God. In most cases, it is used to show God’s aid, favor, leadership or even mentorship to his people. Usage in the Old Testament In the Old Testament, the word â€Å"help† appears several types and is used to mean the role of God in sustaining his people, protecting them from bad events and enemies and guiding them through difficult times. I t first appears in Genesis 4:1 where Eve says, â€Å"I have received a child with God’s help† Usage in the New Testament In the Old Testament, the word is widely used in reference to any type of aid that a person can get from another or from God. It includes material and immaterial aid. For instance, in Luke 4:38, the word is used to mean immaterial aid given to Simon’s mother-in-law, who was suffering.Advertising We will write a custom critical writing sample on Biblical Word Study specifically for you for only $16.05 $11/page Learn More Biblical words related to addiction This section attempts to examine the biblical usage of the words ‘wine’, ‘desire’ and ‘restraint’. The Blue Letter Bible, a resource site that provides links to other bible versions, is used as the primary study material. Wine Wine was a type of alcoholic drink tradition in the Jewish society. In most cases, it is used together with other types of food. However, it was a highly controlled drink because of its alcohol content. In the Old Testament, wine was a common type of drink among the Israelites as well as their neighbors. For instance, in Genesis 14:18, the bible says that Melchizedek, the king of Salem brought bread and wine (NASB, 1995). It shows that wine was a major offering to the Lord. In addition, drinking wine was a form of entertainment and cerebrations (Froma, 2010). Some cases show that drinking excessive wine was considered unholy (Froma, 2010). For instance, in Judges 13:4, the people are advised, â€Å"do not drink wine or strong drink† (KJV, 2000) Usage in the New Testament In the New Testament, it appears that wine was a highly valued product. It was preserved in special wineskins. In Mathew 9:17, the bible says, â€Å"they put new wine in new wineskins and both materials are preserved† (Froma, 2010). For example, in the book of John, Jesus made wine from water and allow people to drink. Nevertheless, it is also considered as a way of destroying the righteousness.† (NKJV, 2011). In other cases, wine is used as a part of treatment given to injuries. For instance, in Luke 7:33, the bible shows how wine and oil were used to treat wounds. Desire The term desire is used to express a number of meanings in the bible. For instance, it is used to show the willingness to obtain something or physical and emotional drive to take an action of fulfills some need.Advertising Looking for critical writing on religion theology? Let's see if we can help you! Get your first paper with 15% OFF Learn More Usage in the Old Testament The word â€Å"desire† is used several times in the Old Testament to express several meanings. A number of instances show that the word means the emotional drive to satisfy some need. The first instance is seen in Genesis 3:16 where women are advised to have a desire for their husbands. Similarly, in Genesis 39:7, Pharaoh’s wife developed a great desire for Joseph and ordered him to have sex with her. In other instances, it is used to show the non-emotional drives to achieve something. For instance, in Deuteronomy 5:21, people are required not to desire other people’s property. Usage in the New Testament The word desire is used to show emotional need to take an action or non-emotional willingness to achieve something. In some cases, ‘desire’ is condemned. For instance, in Colossians 3:5, the bible condemns â€Å"impurity, evil desire, passion and greed because they amounts to idolatry† (NASB, 1995) Restraint This wo rd appears only 4 times in the bible. It is used in both the new and old testament to express different meanings. In the Old Testament It is used in chronicles 28:19, God humbled Ahaz, the King of Israel for his unfaithfulness to the Lord and lack of restraint in Judah. Here, it is used to signify the ability to maintain harmony. This is also seen in Isaih 23:10 Usage in the New Testament It is used to show humbleness and ability to sustain harmony. For instance, in Timothy 2:15, women are advised to â€Å"continue in love and faith and restraint† Core biblical themes Counseling is seen as an important aspect of the Jewish community. God, elders, judges, prophets and priests, provided counseling. In addition, there were two types of help- material and immaterial help. Wine was an expensive but addictive product due to alcoholic content. The bible shows the negative impact of excessive drinking of wine. On the other hand, desire is both an emotional and physical passion to ach ieve something. Emotional desire is condemned in some instances for its ability to lead into sin. Summary Counseling was a part of the society. Every community had specialists who provided counseling while God provided help. Addiction was common and mostly seen in wine drinking and the desire for sexual contact. References American Standard Edition (1901). New York: Thomas Nelson and Sons. Froma, W. (2010). Biblical Facts about Wine: Is It a Sin to Drink Wine? New York: Author House. King James Version. (2000). Edinburg: Thomas Nelson Inc. New King James Version Bible. (2011). Edinburg: Thomas Nelson Inc. Tan, S. (2011). Counseling and Psychotherapy: A Christian Perspective By Siang-Yang Tan. London: Baker Academic. New American Standard Bible (1995). New York: The Lockman Foundation.

Commercial Law Master Case Study Example | Topics and Well Written Essays - 1000 words

Commercial Law Master - Case Study Example For the first dispute of withholding payments due to Gilfil plc, the company can proceed against Tryan in the England & Wales High Court (commercial) without approaching the respective county court since value of claim would exceed 25,000. See relevant case Dalkia Utilities Services Plc v Celtech International Ltd [2006]1 Civil cases at first instance are heard in the County Courts (for minor claims) or the High Court, which is divided into three divisions: Queen's Bench, Family and Chancery. Cases may be appealed to the Court of Appeal (Civil Division). Cases may be appealed from the County Court to the High Court2. For the third issue of Gilfil plc having found their suppliers Eliot Electrical contractors infringing their exclusive and patented design of Phoebus brand. in the name of Pharos, they may file a suit against them in the respective Patent County court. See case 3 Gilfil plc may also implead Barton and Tryan for having sold duplicated version of their Phoebus brand. For the issue of negligent delivery of goods by the carriers, Gilfil plc may file a suit against them in the county court or High court depending up on the value of the claim. In the event of claim exceeding 25000, they can be made a party in the case they are filing against Tryan. Dispute resolutions As for withholding of payment for bills for which goods have been satisfactorily supplied, clause 3(2) of the contract says that order shall be placed on a monthly basis for the entire duration of the contract. The buyer having failed to do so, the seller had every right to repudiate the contract for the reasons of breach. But the seller has not given 30 days notice of its intention to cancel the contract as provided in clause 11 (1) of the contract. It only says 'may" and not "shall" which means notice is not mandatory in the event of a breach. Clause 11(2) will not apply since it is attracted only if there has been no breach in which case notice is construed as mandatory by the words "shall". Clause 5(6) of the contract says that payment shall not prejudice the right of the buyer. In the first place there was a breach on the part of the buyer by failure to place orders because of which the seller later declines to supply for having up other contracts. The breach though may be due t o restructuring, the buyer can not invoke "force majeure" clause nor had they notified the seller about their intention not to place orders temporarily. Where as clause 5(6) payment of any bill does not affect buyer's right under the contract, they have no case to withhold payment of the bills duly supplied. Even if it happens to be the bill goods of which have been damaged in rain, the buyer has no right to do so due to insurance clause. And even otherwise, they failed to receive the goods when it arrived and carriers have done the best possible option available to them, though

Should students use citation Research Paper Example | Topics and Well Written Essays - 1500 words

Should students use citation - Research Paper Example In learning institutions, students should be encouraged to come up with their pieces of work. For the world to progress there is a need for more innovations and creative ideas. Through plagiarism, students will not realize their potential. From my own understanding of plagiarism, I consider it as an offense since a student who is involved in plagiarism does not understand the dangers. Further still, I believe that a student with the act of copying other people’s ideas does not allow the learning process to take place. As such, the transfer of knowledge is limited since whatever they present for assessment is not their work. It thus becomes hard for the examiner to gauge the student’s capability. In view of this, the essay critically discusses the statement â€Å"should students be punished when they plagiarize† through analyzing the opposing and supporting side. With the development of technology, copy and pasting an author’s work has been made easy for students. Some of the students end up copy pasting even an entire work of authorship even without giving credit to the authors. To curb plagiarism, students should be made to understand that, they attend colleges and universities so that they make the world a better place. Coming up with your work as a student, encourages creativity and innovation. Students must identify the gaps that exist in the academic field and come up with ways of filling them. Through plagiarism, a student concludes that they cannot come up with their ideas to increase knowledge in the academic field. In learning institutions, students are expected to give original work to their teachers or lecturers. There is a need for integrity, and most of the learning institutions promote academic honesty (Roig, 2010). Apart from Copy and pasting, there are other forms of plagiarism. There are other forms of plagiarism which most of the times they are overlooked. Submitting an assignment that one has not done is a form of plagiarism. The

Leadership In Toyota Business

Leadership In Toyota Business Transformational Leadership The transformational leadership is the style of the direction in which the chief identifies the change necessary, creates a vision to direct the change with the inspiration, and carries out the change with the commission of the members of the group. Transactional leadership The transactional leadership is a term used to classify the theories formally sweat of a direction of the group which of research the interactions between the leaders and the followers make. A transactional leader is centered more one series of transactions. This person wishes to supervise towards was, to have exchange it profits with its subordinates and clarifies a direction duty with the rewards and the punishments to achieve goals. Charismatic Leadership The charismatic leadership is direction based the capacity of the chief to communicate and to be comprised manners that reach the partisans in a manner basic, emotional, to inspire and to justify. It is difficult to identify the characteristics which make with charismatic leader, but includes certainly the capacity to communicate in an emotional level very with long range, and probably includes some characteristics of the personality. Level 5 Leadership Level 5 leadership has higher level in a hierarchy of the executive capacities. The leaders in the others four levels can be right, but cannot rise with companies of the mediocrity to constant excellence. The direction of level 5 defies the catch of load that to transform with companies of what is good with large it asks chiefs. The chiefs who came towards outside in cover in the study five years from Hakes were relatively unknown out of their industries. The results appear to indicate a change of the emphases far from the hero to with what is anti-hero. Transactional leadership in Toyota Toyota provides like various example of the direction. Toyota led its success by producing a product of higher quality with the assistance of its suppliers. The company works openly with its dominant suppliers to put and increase its operation in execution. It shares the secrecies of the system of production of Toyota with the suppliers to help to reach the operation of quality and the cost which benefits all the members from the chain from source. Toyota grew at fast intervals for this period and it changed recently the third automaker more of large the world. The volume of research suggests that the chiefs transformational (Toyotas of the world) exceed with compromise chiefs (GMs) in the majority of the cases. The example conveys industry shows this on a wide timeframe. The representatives of the chain of source can wish to evaluate their own organizations and to determine the type of direction, and the ship of the partisan, currently while occurring and to make their plans related in the long run consequently. Toyota has a strong capacity of research and development as well as the capacities of manufacture being given its capacity to nourish and preserve creativity of the employee. Also, it provides flexibility in an atmosphere of the work which enough rigid and controlled. Without importing the aforesaid advantage, however, the transactional leadership has disadvantages. This conformity and a highly structured atmosphere, of the employee of the values of the model of the direction cannot often encourage creativity or the innovation of the employee. In addition, this conformity of the employee can far causing more the problems for an organization. New processes, practical, or direct structures which change the nature of directing work, suggest that it can be the important source of the competitive advantage. In this study, hearth in the innovation of management in the level of the organization and fact of research on role of the behavior of direction like antecedent of the key. Being given it prominent role in organizations, management higher than the capacity to influence the innovation of management largely. The belief, behaviors, and the capacities of the expert leaders in the mean system of management arise on the other hand and they are shown to be remarkable different from that one had by the expert representatives in conventional practices of management. The results illustrate important limitations of the models of the capacity of the direction. The development of the new capacities of the direction reframed as problem of changes-over. Gathered with kaizen, capacities that a better service the interests of a business an d its holders of dominant bets can be observed more with effectiveness. The transactional leadership with the attention with the supervision and the reinforcement behaviors of the safety of the workers were shown to be effective in the level of supervision. The average representatives need to be implied in safety and to support the opened communication, while they ensure conformity with the systems of safety. They must not prohibit with supervisors with the degree of autonomy for the initiatives of safety. The larger representatives have an influence first in the culture of the safety of the organization. They need continuously to show a commission visible with safety, indicated him better possible for the moment when they devote to the topics of safety. Give the transactional leader energy to carry out certain tasks and to reward them or to punish them by the operation of the equipment. It gives the opportunity to the person charged to lead to the group and the group decides to follow his led it to obtain an objective predetermined in exchange of a little more. Energy is given to the chief to evaluate, correct and to form with subordinates when the productivity is not until the desired effectiveness of the level and the reward when the result envisaged is reached. The transactional leadership is frequently occupied needs and instrumental or daily transactions of management (i.e. responsibility for operation or work, exchanging a favor, turning over a request) between the chief and the partisans to achieve goals of the subunit. However, the process with effectiveness to handle these needs which face is in accordance with the capacity of diagnosis and with the adaptability of the chief in style of direction. The transactional leadership is perceptibly connected with results of the leadership of the effectiveness of the leader, additional effort of the employees, and satisfaction of the employee. The transformational leadership could increase the transactional leadership to produce of them greater quantities of operation and satisfaction. Transformational leadership in Toyota Toyota uses a program of the management of credit of the vital cycle to protect from the corporative credits. By taking this innovating bringing together, Toyota makes sure that the corporative credits reach or exceed their useful life expectancy. They reached an employers sight of the EC what it can be differed, and for how long, as they estimate the impact of a reserve suggested. With proven results, Toyota revealed strong operation of the credit in a difficult economy by having the information which needs to make suitable adjustments of the percentage of availability and the reductions with their operation project. The transformational leadership functions especially well in the close relations of supervision, compared with more distant relations, and a closer supervision is often more typical in mental adjustments of health. The transformational leadership treats the direction like a characteristic of the personality or predisposition personnel rather which as behavior in which people can be sent. If the capacity to act as a transformational chief is a characteristic then which forms with people in this bringing together it is problematic. The creation of the value for all the holders of bets is still central activities of the units of business. The emphasis is in the improvement supported in the value created, led by all the employees through an integrated system of programs and initiatives, continuously supervised and determined against standards and the measurements put in execution. Division was well carried out in difficult economic circumstances. The transformational chief justifies with his effective and effective equipment to be. The communication is the base for the achievement of the objective which is centered with the group the final desired achievement of the result or the objective. This leader is highly visible and uses the chain of the commando to obtain made work. The transformational leaders are centered the large table, by needing some to be surrounded by people who take the care of the details. The chief always seeks the ideas which move the organization with the range the vision of the company. The representatives who exert practices transformational of the direction will most probably test higher tendencies for the commission of emotional and normative organization. The commission of organization of handling of the employee is important because it was related to the reduced volume of sales, with the increasing knowledge which he shared, with the increasing behaviors of organization of the citizenship and with the reduced absenteeism. The transformational leadership is different from the compromise direction because it is not inculcated in the cognitive spirit. There are some rules to put the model transformational direction in execution. These rules include the articulation of light and an attractive vision, by explaining how the vision can be obtained, to act sure and optimistic, by expressing confidence of the partisans, by using the dramatic actions, symbolic systems to accentuate the dominant values, and to lead them for example. The transformational leadership contributes to the innovation of management. Interesting, our study indicates that one smaller, less complex, favors organizations more compromise direction to carry out the innovation of management. In addition, of the larger organizations require to draw in transformational chiefs to compensate for their complexity and to allow that the innovation of management thrives. Charismatic leadership in Toyota Toyota can internally be seen like modern institutional manner, by preserving energy dynastic. In Kiichiro Toyoda in 1937 it founded with the company like effect of industries of Toyota of the company of his father, and chair it today is Akio Toyoda. It would be large over-simplification to assume which a family-based structure inhibits the change and the adjustment. However, its response to its manufacture and recent problems of the strategy appear constant with a tendency to avoid the radical actions which seem threats to remove the heart with cultural values. The charismatic leaders create a direction of the goal for their organization which is of motivation and inspiring. The charismatic chiefs express things simply so that each one obtains it; they use the positive language, often stories of the use, symbols, and metaphors to obtain its point with crossing. The charismatic chiefs ask for the status quo, take risks and thrive in the innovation and change them. But in the other side it can be deprived spectacular, it creates a worship of the personality and can use towards outside with the workers. Toyota tries to balance the interests of what are stakeholders like employees, customers, suppliers, investors and the Community with the mean production. Use factors as quota of market; the product or the innovation of the service, quality etc are regarded as important parts of the total value of the business. The Charismatic leadership strongly has its effects by contracting the concepts of itself of the partisans to the interest of the mission articulated by the chief like, the (A) the behavior of charismatic chiefs and its effects the partisans, it (b) the role of the values and the orientations of the partisans in the charismatic relation, and it (c) something of the conditions of organization which support the appearance and the effectiveness of charismatic chiefs. The charismatic leaders act like model of the role for the followers, show the individualized consideration and recognize the realization of the partisan, exhibit not very conventional behavior, and show the personal risk with regard to their vision for the organization. The charismatic leader led to the investment growing in the signature, and influences it of the chief were taller when the prospects for a return of organization were more difficult. The transformational leadership provides partisans a clear direction of the goal which, is a model of the role for control moral and built the identification with the leader and his vision articulated for a sector. Level 5 leadership in Toyota Leadership, leading the organization to a vision which uses a tactical strategy definite business and directions through all the levels on the floor of the plant, fact TPM, inclination, and the vision of the work management of TPM for TPM must be aligned levels themselves higher of the organization on the floor and the suppliers of the plant. The level 5 leadership is the category of execution higher than the direction in world. They can reach splendid and durable results in the long run. With the force requires much time and personal investment of the leader but the leader does not receive personal credit. The level 5 leadership defies the catch of load that to transform with companies of what is good with large it asks chiefs. Tri-dimensional leadership in Toyota Toyota is installed in what calls the base the three-dimensional chief the dynamic operational ones of the success (COSD) which makes the culture of a large company. Since a particular system of values is the angular stone of one of highly of collaboration, and cross-pollinated, culture which gains, required PO to support with responsible representatives to carry them ahead, while ensuring itself whose behavior of the employee is constant with them. In this model, the measure of the efficiency is an evaluation of the response to the atmosphere or the results, rather which an evaluation of the initial behavior of the leader. Emotional Intelligence One defines the emotional intelligence as timidity a person, a confidence in itself, self-control, commission and integrity, and the capacity of a person to communicate, influence, and start the change and to accept the change. Three of the aspects more important than the emotional intelligence so that the capacity of a chief makes effective decisions are timidity, communication and influence, and commission and integrity. Three dominions of the capacity-emotional ability (which call EQ), the intellectual capacity (index of intelligence), and the direct capacity (MQ) which contributes to operation in the act included the supervision, the oral communication, the direction of the business, even management, and the initiative and independence. The index of intelligence is EQ, not which is given as good somebody will be carried out in work. While this does not mean that the technical abilities and the general intelligence must be made case, some studies indicated that the emotional intelligence twice is so important. When it comes to the direction, I.E. (internal excitation) is incredibly important, while differentiating between the effective and poor direction. Toyota, which invented the system of the mean production, appears to have inclined its manner with the catastrophe. The pressures to increase margins led to a series of decisions to cut a little cost to one here and a bit there in the process of the design. While each individual decision was probably justifiable, the cumulative impact appears to have made the increase in the cars of the company the fragile or fragile systems, ripe for the unexpected forces like the interaction between a carpet the stage and of an accelerator to involve a judgment of the system. While the exploration and the exploitation of knowledge represent two different activities which require corresponding adjustments of organization, the development of new product calls for a dynamic combination from both. In agreement with a systematic revision of the paradox between the exploration of knowledge and the exploitation and several strategies of resolution, research extends the construction of the ambidexterity of organization of the double structure to the ambidextrous capacities, and suggests a dialectical method to reconcile this paradox on lower levels of organization. Current requirements of leadership The development of the theory of the leadership was parallel to the development of the theory of organization. The models of the direction of liberalism, compromise and transformational explain the old paradigm of the bureaucratic organization and reinforce the new paradigm of organization for the twentieth first century. The bureaucratic organization is analyzed in terms of direction the liberalism and the compromise elements of the direction of management-by-the exception and the reward quota. The new station-bureaucratic organization is analyzed in terms from four I of the direction transformational: individualized consideration, intellectual stimulant, motivation of what is inspirational, and influence idealized. The inferences are drawn for the roles and the necessary behavior of the future chiefs. Challenges faced by leader The leader and the organization face today with a host of the challenges of the direction. These challenges are of dropped natural. 1) Transformation: The transformation changes a long-term reality instead of work of today. The technology which it changes and a total economy are two of the principal factors, with to which the leader must face. The best put plans stops organization a structural change is frequently undermined by a lack to exist strong direction. Sail so much successfully with leaders of the transition and the organization needs to include/understand the human side of the transition and to build a culture of confidence. Like such a leader need has to want to explore and learn how from its own emotional transitions to support such efforts in others. 2) Cultural adaptability: The cultural adaptability is the goodwill and the capacity to recognize, include/understand and work with effectiveness through cultural differences. These differences can include language, the religion and with social customers, among others. While the organization arrives at being more total, the cultural adaptability changes a vital ability for directing success. 3) Management of the conflict: The difficult interactions, the dissimulated end of the organization like, the tensions and frustration can all the release of conflict in the place of work. The conflicts in progress can sabotage productivity, the co-operation and the communication. However, when the leaders handle conflict with effectiveness, the organization can test positive advantages, like decision-making better, more open and an ambient organization which stimulates creativity and the innovation. To handle conflicts, the chiefs need to learn how to recognize it and then to treat it. 4) Effective relations of the emotional intelligence: The emotional intelligence is more than hardly a word of the buzz. It is in the base of the capacity of a leader to put in connection well with others the chiefs it cannot produce the alignment of the commission and cultivate it necessary to survive and thrive at complex times. The capacity to build effective relations is one of the more important dominant components challenges of the direction. Future requirements of leadership The analysis of future condition of the direction determines the necessary critical capacities leaders to deliver in the future strategy of the organization. Once these capacities of the direction are identified, they are useful as the foundation for the significant process of the hour which must be aligned with the tools and the processes for development of the direction to deliver to the necessary leaders to carry out the future strategy. Only if the analysis of the future conditions of the direction is precise will that the remainder of the system of development of the direction is built with effectiveness and contributes to the future success of the organization. Future leader face the challenges Being given the dynamics of the business which it changes, we must start to seek new manners of developing abilities of the direction to contribute to chiefs successfully to sail the future challenges. The popular publications of business are centered in design and the innovation like contributor dominant with the success of long-term organization. 85 percent of larger leaders it were appropriate that the virtual direction is an ability necessary for the chiefs in its organizations and as agreed as the virtual direction requires various abilities which it expensive direction with face. The leaders must learn how to work through limits to collaborate with effectiveness during the years which come. Confidence and the respect are vital in the place of work, to develop these abilities for the future it will be essential to maintain with the committed and trustful labor on the long term. The development of the talent is a challenge of important organization today. The differences in the answers could be allotted to the fact that one communicated no plan of the succession by the means of organizations. The direction and the success of organization will require greater levels of the operation of each employee. To ensure we are ready for the challenge, health and the aptitude must change a hearth of our processes of the development to be dealt with the high voltage, to avoid burnout, and to maintain with completely engaged employees. (CEML): Best Practice Guide for Organizations for leadership development The Council for Excellence in Management and Leadership (CEML) to help in the United Kingdom to improve their action of the representatives and the chiefs of good quality. This particular project was directed the improvement of the direction in large corporations and was directed by a group of operation understood by the directors or executives which revealed in the principal Councils with such a responsibility. Developing leaders Who convert need hour to develop its capacities. The effective chiefs are use with models, trainers, mentors, the cars and the advisers of the role to improve. The legendary direction is reached by which they seek wisdom and knowledge their advisers, of partisans and professors. The courses of training of the abilities of the direction build their confidence and authorize their dash towards success. Leadership training programs energizing people of the organizations. The development of the direction follows and to form workshops must consolidate its capacity, align its values with authentic behaviors and enable him to attend its professionals, executives; the representatives and the heads of undertaking obtain their objectives. The development of the leadership is recognized like vital ingredient for the success of the organization, the implication of larger leaders in teaching and to learn from the future leaders was shown to be a tool with long range and effective. The leadership is to gauge the energy level of chiefs as it makes them able to learn its errors and from entertainment to be had in the place of work. The academician can make enormous contributions in the knowledge and the abilities of people who convert put in connection with the Community and the social change. Mentorship and to model role played a significant part in its development of career. Mentoring is a form of social assistance in which they match with an experienced individual and quite less informed (it protects) in order to advance the satisfaction of the development and the career of they protects and decreased alienation work, the effective socialization of the young employees, promotions and remuneration, mobility career and advances, satisfaction of the career, commission of the career, job satisfaction, and reduced to the individuals with an experiment and a knowledge of more advanced (mentors) tension of work. (CEML): Best Practice Guide for Organizations for future leadership development The Council for Excellence in Management and Leadership (CEML) to make sure that Great Britain can produce with chiefs and representatives of the future in the public and private sectors which are phosphorus for any person in the world. This will be based the following strategy of the three-filament: à ¢Ã¢â€š ¬Ã‚ ¢ To improve the request for the development of management and the direction of individuals and organizations; à ¢Ã¢â€š ¬Ã‚ ¢ By improving the source and the delivery of the abilities of management and the direction by proposing reforms with the source of education of management and direction and the drive; à ¢Ã¢â€š ¬Ã‚ ¢ The supervision not-changes in connections between the request and the source the creation of the CEML shows clearly not only the attempt of the current administration to deliver to improve the development and the drive of it of the direction of the public sector, but also that which started to develop some of the strategic structures to deliver with an aim. The CEML is clearly necessary a prospect for the government to direct, contract and improve the development of the direction and management in the organizations of the United Kingdom.

Compare and Contrast Driving in the Winter and Driving in the Summer

New drivers may believe that driving an automobile is similar in every season, but experienced motorists are likely to know that winter and summer offer different pleasures and challenges. The most obvious daistinctions between the seasons are the temperature, precipitation and amount of daylight. Each of these variables can change driving conditions dramatically. Indeed, some drivers even refrain from driving in certain weather. Fortunately, both seasons do have advantages so drivers can enjoy the road if they respect the effects of different seasons. Summer heat is cause for caution. Drivers must beware of blinding sun and take care to use sunglasses or pull down visors. Hot, humid weather may also cause windshields to fog up. Using air conditioning to maintain comfortable environment for passengers and pets is also often sensible. Parents may also find melted crayons or plastic toys if the car is left in the heat too long. On the other hand, leaving the air conditioning on too long can even cause the car to overheat. Additionally, the temptation to take long drives may lead to driver fatigue. All of these potential hazards mean drivers should be careful driving in the summer. While summer heat can be difficult to cope with, winter weather including rain, dark skies and hail or snow storms are sure to challenge even the most experienced drivers. Drivers often experience limited visibility during precipitation or heavy fog, which requires them to slow down or even wait out the worst weather. Special equipment such as chains may be needed. Another difficulty is the potential for cars to freeze overnight. Drivers must also watch out for icy on roads that can cause skidding and accidents. Summer and winter can both cause dangerous conditions; however, there are opportunities to enjoy the open road in both seasons. Summer allows time for leisurely drives with high visibility, mild weather and to special destinations such as the beach. Roads that may be impassable in the winter are typically open in the summer as well so that drivers can enjoy unusual terrain. In contrast, while winter driving may be limited by less light and harsher weather, driving through a snowy landscape or holiday light displays are uniquely beautiful experiences. Further, winter driving is associated with Thanksgiving and Christmas gatherings that reunite families. It is clear that in rain or shine, there are risks and rewards to taking to the road.

Mgt 445 Week 5 Individual Assignment: Article Analysis

A negotiation is a civil process that takes place to resolve and develop a solution between all parties involved. Negotiations take place between all types of parties; organizational and global. They are structured to resolve the situation in an orderly manner with steps and strategies. In 2003, a global situation occurred that required negotiation between countries. North Korea announced they were withdrawing from the nuclear non-proliferation treaty (NPT). Upon making this announcement, they also stated they do not intend on producing nuclear weapons.This information was revealed from the official North Korean News Agency, NKNA. When this was announced, it raised red flags around the world. Even though North Korea declared the withdrawal immediate, according to Article X, countries must give a three month notice before withdrawal. North Korea made the decision to withdraw from the NPT is based on Bush’s 2003 State of the Union Address, when he declared North Korea to be part of the ‘axis of evil’ along with Iran and Iraq (Global Issues, 2006).Since the United States were preparing to invade Iraq, they felt they needed to create a credible deterrent in case they were next. The non-proliferation treaty was developed to convince countries such as Argentina, Brazil, Germany, Japan, South Africa, South Korea, and North Korea to be non-nuclear countries. The treaty was enforced in 1970 and provided the framework needed to prevent the spread of nuclear weapons. A decade before in 1993, North Korea threatened to withdraw from the NPT.There were several bilateral negotiations that took place resulting in North Korea retracting their statements just a few days before the withdrawal became effective. Since North Korea was no longer an official member of the treaty, there were few obstacles stopping them from developing and selling nuclear weapons, technology, and materials to other countries. There are only a few countries that are not members of the NPT. These countries are India, Pakistan, Israel, and North Korea. There were several key factors in this initial negotiation of nations.In order to prevent other countries from evaluating their stand on the NPT, the Bush Administration developed a new approach to global security. Several key global arms control agreements were implemented, these agreements included the Anti-Ballistic Missile Treaty, the Biological Weapons Convention, the Comprehensive Test Ban Treaty, the Sort Treaty, and the process of strategic arms reductions with Russia (Global Issues, 2006). When North Korea decided to withdraw, they invoked their legal right to do so.The United States was worried that this action would increase international tension and risk Japan evaluating their position on nuclear weapons. Bill Richardson acted as a mediator between the United States and North Korea. After several discussions and negotiations, North Korea said they would halt all nuclear weapon developments. Shortly after making this agreement, they restated saying they would not give up their nuclear weapon program until the United States provides it with a civilian nuclear reactor.These actions made provisions for the entire treat to be reviewed, revised, and negotiated between countries. Actions or comments made by countries caused commitments to a nuclear weapons treaty to be revoked. This is a serious and sensitive subject globally and a nuclear war is feared by every country and their leaders. The same steps of negotiation are used in a global topic such as nuclear weapons and the NPT and it would be in an organizational negotiation.When these steps are carefully followed and sometimes calling in a third party mediator is necessary, a solution can be developed and implemented for the sake of all parties involved. References CNN World. (2003, January 10). Retrieved from Nuclear Weapons: North Korea Leaves Nuclear Pact: http://articles. cnn. com N Korea Withdraws From Nuclear Pact. (2003, Januar y 10). Retrieved November 9, 2012, from BBC News World Edition: http://news. bbc. co. uk/2/hi/asia-pacific. com Global Issues. (2006, October 26). Retrieved from North Korea and Nuclear Weapons: http://www. globalissues. org

Glycoprotein Definition and Function

A glycoprotein is a type of protein molecule that has had a carbohydrate attached to it. The process either occurs during protein translation or as a posttranslational modification in a process called glycosylation. The carbohydrate is an oligosaccharide chain (glycan) that is covalently bonded to the polypeptide side chains of the protein. Because of the -OH groups of sugars, glycoproteins are more hydrophilic than simple proteins. This means glycoproteins are more attracted to water than ordinary proteins. The hydrophilic nature of the molecule also leads to the characteristic folding of the proteins tertiary structure. The carbohydrate is a short molecule, often branched, and may consist of: simple sugars (e.g., glucose, galactose, mannose, xylose)amino sugars (sugars that have an amino group, such as N-acetylglucosamine or N-acetylgalactosamine)acidic sugars (sugars that have a carboxyl group, such as sialic acid or N-acetylneuraminic acid) O-Linked and N-Linked Glycoproteins Glycoproteins are categorized according to the attachment site of the carbohydrate to an amino acid in the protein. O-linked glycoproteins are ones in which the carbohydrate bonds to the oxygen atom (O) of the hydroxyl group (-OH) of the R group of either the amino acid threonine or serine. O-linked carbohydrates may also bond to hydroxylysine or hydroxyproline. The process is termed O-glycosylation. O-linked glycoproteins are bound to sugar within the Golgi complex.N-linked glycoproteins have a carbohydrate bonded to the nitrogen (N) of the  amino group (-NH2) of the R group of the amino acid asparagine. The R group is usually the amide side chain of asparagine. The bonding process is called N-glycosylation. N-linked glycoproteins gain their sugar from the endoplasmic reticulum membrane and then are transported to the Golgi complex for modification. While O-linked and N-linked glycoproteins are the most common forms, other connections are also possible: P-glycosylation occurs when the sugar attaches to the phosphorus of phosphoserine.C-glycosylation is when the sugar attaches to the carbon atom of an amino acid. An example is when the sugar mannose bonds to the carbon in tryptophan.Glypiation is when a  glycophosphatidylinositol (GPI) glycolipid attaches to the carbon terminus of a polypeptide. Glycoprotein Examples and Functions Glycoproteins function in the structure, reproduction, immune system, hormones, and protection of cells and organisms. Glycoproteins are found on the surface of the lipid bilayer of cell membranes. Their hydrophilic nature allows them to function in the aqueous environment, where they act in cell-cell recognition and binding of other molecules. Cell surface glycoproteins are also important for cross-linking cells and proteins (e.g., collagen) to add strength and stability to a tissue. Glycoproteins in plant cells are what allows plants to stand upright against the force of gravity. Glycosylated proteins are not just critical for  intercellular communication. They also help organ systems communicate with each other. Glycoproteins are found in brain gray matter, where they work together with axons and synaptosomes. Hormones  may be glycoproteins. Examples include human chorionic gonadotropin (HCG) and erythropoietin (EPO). Blood clotting depends on the glycoproteins prothrombin, thrombin, and fibrinogen. Cell markers may be glycoproteins. The MN blood groups are due to two polymorphic forms of the glycoprotein glycophorin A. The two forms differ only by two amino acid residues, yet that is enough to cause problems for persons receiving an organ donated by someone with a different blood group. The Major Histocompatibility Complex (MHC) and H antigen of the ABO blood group are distinguished by glycosylated proteins. Glycophorin A is also important because its the attachment site for Plasmodium falciparum, a human blood parasite. Glycoproteins are important for reproduction because they allow for the binding of the sperm cell to the surface of the egg. Mucins are glycoproteins found in mucus. The molecules protect sensitive epithelial surfaces, including the respiratory, urinary, digestive, and reproductive tracts. The immune response relies on glycoproteins. The carbohydrate of antibodies (which are glycoproteins) determines the specific antigen it can bind. B cells and T cells have surface glycoproteins which bind antigens, as well. Glycosylation Versus Glycation Glycoproteins get their sugar from an enzymatic process that forms a molecule that would not function otherwise. Another process, called glycation, covalently bonds sugars to proteins and lipids. Glycation is not an enzymatic process. Often, glycation reduces or negates the function of the affected molecule. Glycation naturally occurs during aging and is accelerated in diabetic patients with high glucose levels in their blood. Sources Berg, Jeremy M., et al. Biochemistry. 5th ed., W.H. Freeman and Company, 2002, pp. 306-309.Ivatt, Raymond J. The Biology of Glycoproteins. Plenum Press, 1984.